T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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EM 302 Thin Skin
Hemi-Desmosomes
Grayscale Color
Skin consists o a superficial epithelial component, the epidermis, and underlying connective tissue components, the dermis and hypodermis
Hemi-desmosomes (#1, #2) firmly attach the epidermis to the underlying basal lamina. The hemi-desmosomes themselves are attached to intermediate filaments (i.e., keratin) in the basal layer of cells.
The basal lamina is integrated into the matrix of dermis with many anchoring fibrils.
A small, unmyelinated nerve fiber is seen very close to the epidermis.