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CHAPTER 17 - RESPIRATORY SYSTEM
Histology Guide
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Fig 013 Respiratory System
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T. Clark Brelje
University of Minnesota
Minneapolis, MN

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University of Minnesota
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Robert L. Sorenson, Ph.D.

University of Minnesota
Department of Genetics, Cell Biology and Development
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Minneapolis, MN 55455

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Fig 013 Respiratory System

Respiratory System

The respiratory system is a series of organs responsible for taking in oxygen and expelling carbon dioxide.

  • Nasal Cavity - moistening and filtering of air
  • Pharynx - part of throat behind the mouth and nasal cavity and above the esophagus and the larynx
  • Larynx - splits from the pharynx and leads into the trachea
    • Vocal Cords - generate sound by vibrating
    • Epiglottis - helps close the air conducting passage way during swallowing
  • Trachea - supported by C-shaped hyaline cartilage rings
    • Respiratory epithelium
  • Primary (Main) Bronchi - branches into the left and right lungs and is supported by hyaline cartilage
    • Respiratory epithelium
  • Lungs
    • Bronchioles
      • Simple ciliated columnar (or cuboidal) epithelium with Club cells
    • Terminal Bronchioles
      • Simple ciliated columnar (or cuboidal) epithelium with Club cells

Conducting Passages

Conducting passages convey air into the respiratory passages.

  • Trachea - fibromuscular tube supported by hyaline cartilage
    • Respiratory epithelium
  • Primary Bronchi - branches into the left and right lungs
    • Respiratory epithelium
  • Secondary Bronchi - multiple branches from the primary bronchi within the lungs
    • Simple ciliated columnar (or cuboidal) epithelium with Club cells
  • Bronchioles - multiple branches from secondary bronchioles within the lungs
    • Primary Bronchioles
    • Terminal Bronchioles

Respiratory Passages

Respiratory passages are involved in the exchange of oxygen and carbon dioxide within the lungs.

  • Respiratory Bronchiole - gives rise to two or three alveolar ducts
    • Simple ciliated columnar (or cuboidal) epithelium with Club cells
  • Alveolar Ducts - through fares lined by alveoli and terminate into alveolar sacs
    • Simple squamous epithelium
  • Alveolar Sacs - round spaces with openings into alveoli
  • Alveoli - pockets that open into alveolar sacs
    • Type I pneumocytes - simple squamous cells responsible for gas exchange
    • Type II pneumocytes - produce and secrete surfactant
    • Alveolar macrophages - phagocytic cells observed in the alveolar spaces
© 2005-2026. T. Clark Brelje and Robert L. Sorenson