Each slide is shown with additional information to its right. The image can be changed using any combination of the following commands.
Sidebar
Click on links to move to a specific region.
Click on images to show that view.
Use the toolbar to change the magnification and pan the displayed image.
Mouse
Click to zoom-in
Double-click to zoom-out
Alt-click to zoom-out
Alt-double-click to zoom-out to the entire slide
Drag the image to pan
Keyboard
Shift or ‘A’ key to zoom-in
Ctrl or ‘Z’ Key to zoom-out
Arrow Keys to pan across the image
ESC key to zoom-out to the entire slide
Touch
Tap to zoom-in
Double-tap to zoom-out
Alt-tap to zoom-out to the entire slide
Drag the image to pan
SHARE
A link to a virtual slide can be saved for later viewing in different ways.
Clipboard
The address of this view has been copied to your clipboard. This link can be pasted in any other program.
Bookmark
A bookmark link can be created using the bookmark function (Ctrl-D for Windows or Cmd-D for Mac) of your browser. Choose a name for the bookmark and select the folder in which you want it saved.
Because mitochondria are rod shaped and only 0.1 to 0.2 µm in diameter, they are at the resolution limit of a light microscope. However, mitochondria were described by staining with iron hematoxylin many years before they were studied by electron microscopy. Today, this technique is primarily of historical interest because of the availability of mitochondria-specific vital dyes and antibodies.
Small Intestine
It’s relatively easy to see mitochondria in the cells lining the small intestine. Examine the surfaces of villi within the cross section of the intestine.
Mitochondria can be distinguished as darkly stained, thread-like structures in the apical cytoplasm of some cells. They appear as dark grey lines that run parallel to the long axis of the cell and perpendicular to the cell surface.
The Golgi apparatus is visible as an unstained region adjacent to the nucleus.
These cells are polarized with their basal surface resting on the underlying connective tissue while the apical surface faces the lumen.
Liver
The liver is composed primarily of hepatocytes. Examine individual hepatocytes at high magnification.
The cytoplasm is filled with so many mitochondria that it is difficult to distinguish them individually. The mitochondria are thread-like or granular depending on their orientation.
Although the nucleus does not stain, the nucleolus is prominently stained. Some of the cells have more than one nucleolus.