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Platelets are small cell fragments produced by budding from megakaryocytes under the influence of thrombopoietin. Each megakaryocyte produces between 5,000 and 10,000 platelets.
Platelets are much smaller than red blood cells.
Small discs (2 to 4 µm diameter)
No nucleus
Central region is basophilic structure (granulomere)
Platelets are involved in the formation of blood clots. Too few platelets can cause excessive bleeding, while too many platelets can cause blood clot formation. Their life span is between 7 to 10 days.
Eosinophils kill multicellular parasites and phagocytose immune complexes. They circulate in the blood for 8 to 16 hrs and survive in peripheral tissues for only 2 to 5 days.
Lymphocytes are released from bone marrow into the peripheral circulation. They exit blood into one of the peripheral lymphatic organs and continue to divide.
Monocytes are released from the bone marrow into the peripheral circulation. Their time span in blood is only 16 hrs. Monocytes in connective tissue differentiate into macrophages.
Monocytes are involved in phagocytosis and antigen presentation.