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CHAPTER 14 - GASTROINTESTINAL TRACT
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MH 116 Gastroduodenal Junction
TISSUE
Junction between Pyloric Stomach
and Duodenum of Small Intestine
(monkey)
STAIN
Hematoxylin & Eosin
FIXATIVE
Zenker's Formaldehyde
IMAGE SIZE
79,943 x 14,660 pixels
4.4 GB
FILE SIZE
131 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Department of Genetics, Cell Biology, and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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University of Minnesota
Department of Genetics, Cell Biology and Development
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MH 116 Gastroduodenal Junction

Gastroduodenal Junction

The is the boundary between the (left) and the (right) of the small intestine. The pyloric sphincter controls the passage of chyme from the stomach into the duodenum.

The stomach and the duodenum are composed of the four layers characteristic of the gastrointestinal tract. However, pyloric glands are located in the mucosae whereas the duodenal glands are located in the submucosa. This can easily be seen by following the muscularis mucosae across the gastroduodenal junction.

  • Mucosa (or mucous membrane)
    • Epithelium - structure abruptly changes:
      • - long pits and short, coiled glands.
      • - broad projections (or villi) and crypts.
    • Lamina Propria - loose connective tissue
      • - found between gastric pits and glands.
      • - forms the core of intestinal villi.
    • Muscularis Mucosae - continuous between the and the .
  • Submucosa - contains in the duodenum.
  • - expands in the stomach to form the pyloric sphincter.
  • Adventitia - absent from this specimen.
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