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CHAPTER 12 - EXOCRINE GLANDS
Histology Guide
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MICROSCOPE SLIDE

SLIDE NAME
MHS 296 Pancreas
TISSUE
Pancreas
(cat)
STAIN
Dye injection
Hematoxylin & Eosin
IMAGE SIZE
47,838 x 23,173 pixels
3.1 GB
FILE SIZE
174 MB
OBJECTIVE
40x
PIXEL SIZE
0.3171 µm
SOURCE
Zoology Department
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

Professor Emeritus
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

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MHS 296 Pancreas

Exocrine Pancreas

Pancreas fixed after perfusion of a dye (red colloid) through the peripheral vascular system. Both the arterial supply and venous drainage of the pancreas are filled with the dye.

Exocrine cells are arranged as acini of pyramidal serous cells (i.e., acinar cells). Each acinus is surrounded by a meshwork of .

  • (longitudinal section) - vasculature similar to acini
  • Intralobular ducts (,) - supplied with their own blood vessels
  • Interlobular ducts (,) - surrounded by an extensive network of blood vessels

The ducts are highly vascularized because they secrete bicarbonate to neutralize acid from the stomach.

The islets of Langerhans (,), are also highly vascularized and receive 5 to 20% of the total pancreatic blood, despite the islet volume being only 1 to 2% of the total pancreatic volume. Unlike acini, blood vessels penetrate into the core of islets.

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